Kyle Fink, Ph.D
Assistant Professor, UC Davis Health System

I am a scientist with a focus on translational research for the therapeutic development of gene modifying modalities such as Zinc Fingers, Transcription Activator-like Effectors, and CRISPR/Cas9 to treat genetically-linked neurodevelopmental disorders. My training and translational research is centered around the interdisciplinary aspects that help to advance novel therapeutics for IND-enabling studies. My key interest in this field involves understanding the therapeutic benefit in human cellular models of disease, functional efficacy in transgenic rodent models, and optimization of delivery modalities in clinically-relevant models. My lab focuses on the therapeutic development of gene modifying modalities to induce epigenetic alterations in CDD through testing in human cellular models of disease, functional efficacy in transgenic rodent models, and optimization of delivery modalities in clinically relevant models. My lab also has experience in generating traditional AAV constructs that can be used for gene therapy for CDD and other neurodevelopmental disorders.