Regina Faubel received her Diplom in Biology from the University of Goettingen, Germany, after which she undertook graduate training in the laboratory of Prof Gregor Eichele, Director of the Max-Planck-Institute of Biophysical Chemistry. It is at the Max-Planck she became interested in studying the role of cerebrospinal fluid in the regulation of brain physiology. This culminated in her dissertation research work uncovering the evolutionarily conserved role of brain motile cilia in generating a fluid transport system akin to a vascular network. This work was published in the journal Science, and for which she also received the prestigious David S. Miller young scientist award by the Blood-Brain-Barriers Society. Since receiving her PhD degree, she joined the laboratory of Dr. Cecilia Lo at the University of Pittsburgh as a postdoctoral fellow, where she is now pursuing studies focused on investigating the biological function of the cilia-driven fluid transport system in the brain. These studies have led her to investigate the potential role of cilia dysfunction in the pathogenesis of CDKL5 deficiency disorder with studies involving both Cdkl5 mutant mice and also patients with CDD.